Senior Process Engineer – Equipment and Systems
Own equipment and manufacturing readiness. Ensure systems, calibration, and uptime support production, solving real problems on the line and keeping operations running reliably.
We usually respond within a week
About the role
We are seeking a Senior Process Engineer – Equipment & Systems to take ownership of manufacturing equipment, facility readiness, and supporting systems within our pilot manufacturing operation. Based at our London site, this is a primarily on-site, hands-on role.
You will be responsible for ensuring equipment is available, reliable, and suitable for manufacturing, while establishing the structures required to support maintenance, calibration, and safe operation.
In the early phase, this role will include active participation in manufacturing activities on the production line, ensuring equipment and facility requirements are aligned with real operational conditions.
Tasks and responsibilities
Own manufacturing equipment performance, availability, and readiness
Establish and manage calibration programmes for relevant equipment
Define and implement preventive maintenance approaches
Lead equipment breakdown response and recovery
Maintain high levels of equipment uptime to support production
Manage equipment status visibility (e.g. calibration, maintenance)
Maintain critical spare parts for key equipment
Support facility readiness, including layout and basic infrastructure
Work with external consultants to support EHS implementation and compliance
Ensure equipment and environment support controlled manufacturing
Work closely with Process Engineering and Operations to resolve equipment-related issues
Participate in manufacturing activities during early pilot phases
Qualifications
Degree in Engineering, Mechanical, Electrical, or related discipline, or equivalent experience
Experience working with manufacturing equipment in a technical environment
Strong understanding of maintenance, calibration, and equipment reliability
Practical, hands-on problem-solving ability
Experience working in structured or regulated environments
Ability to work cross-functionally
Desirable
Experience in regulated industries (e.g. medical devices, biotech, pharmaceuticals)
Experience establishing maintenance or calibration systems
Experience supporting pilot or early-stage manufacturing environments
Experience working with external contractors or service providers
Familiarity with health and safety requirements in technical environments
This is a hands-on role within an early-stage manufacturing team, where you will help build and refine processes based on real operational experience. You will play a key part in establishing robust, scalable systems that will underpin future manufacturing capability.
We offer a competitive salary and benefits package. If you are passionate about building robust manufacturing systems and contributing to the delivery of innovative scientific technologies, we encourage you to apply!
- Team
- Operations - Cartridges
- Locations
- London
About Portal Biotech
Founded by DNA-sequencing veterans, Portal Biotech is developing the first bench-top single-molecule protein sequencer, leveraging machine-learning algorithms and building on decades of in-house expertise in nanopore technology. By analysing full-length protein molecules at the single-molecule level, our platform delivers rapid, real-time information on protein identity, abundance, and structure. Those insights open frontiers in drug discovery, diagnostics, and fundamental research, helping scientists and clinicians to better understand human health and disease.