Director of IT & Security
Build and run the secure internal foundations of a cutting-edge biotech company, protecting data, systems, and workflows in a low-trust environment while enabling fast, reliable scaling.
About the role
We are hiring a Director of IT & Security to design, build, and operate the internal systems and security foundations of Portal Biotech.
This is a hands-on leadership role focused on internal systems, identity, and organisational security.
The role is intentionally centred on building a secure, controlled internal environment that enables rapid and reliable development of our platform, while maintaining clear separation from product and platform engineering responsibilities.
You will take ownership of our internal security posture in a low-trust environment, where sensitive scientific data, proprietary algorithms, and emerging risks — including misuse of AI tools — require strong controls, visibility, and discipline.
Working closely with Engineering, Data, QA/RA, and leadership, you will ensure our internal environment is secure, controlled, and audit-ready, without slowing down the development of our platform.
Tasks and responsibilities
Internal Security & Risk
Define and implement a security-first IT architecture across identity, endpoints, SaaS, and corporate cloud systems
Operate with a low-trust / zero-trust mindset, minimising implicit trust across users, devices, and services
Design and enforce controls to mitigate data leakage risks, including misuse of AI tools and external platforms
Lead threat modelling and risk assessments focused on internal and organisational attack surfaces
Implement monitoring, logging, and alerting for user, device, and SaaS activity
Be Hands-On with Systems
Directly configure and manage:
Identity providers
MDM / endpoint security
Access controls and SaaS configurations
Implement and maintain practical controls such as:
SSO and conditional access
RBAC and least privilege
Device compliance and hardening
Lead incident response for internal security events
Build Secure Foundations for Growth
Establish scalable IT infrastructure supporting company growth and regulatory expectations
Implement asset management, access reviews, and lifecycle controls
Ensure systems are audit-ready with strong traceability
Support compliance with frameworks (ISO 27001, Cyber Essentials plus, GDPR, etc.)
Define and Enforce Practical Policy
Develop enforceable policies for:
Acceptable use (including AI tools)
Data handling and classification
Identity and access management
Ensure policies are grounded in real workflows and actively enforced
Deliver lightweight training to embed secure behaviours
Partner Across the Organisation
Work closely with:
Engineering leadership on shared infrastructure boundaries
Data teams on secure data access and handling
QA/RA on compliance and audit readiness
Legal on data protection and risk
Act as the internal authority on organisational security and IT risk
Qualifications
Essential
Strong hands-on experience in IT and security (identity, endpoints, SaaS, cloud)
Experience operating in low-trust or high-sensitivity environments (biotech, fintech, defence, healthcare, etc.)
Proven ability to implement practical, enforceable security controls
Deep understanding of identity and access management (SSO, RBAC, least privilege)
Experience with endpoint security, MDM, and device management
Strong knowledge of cloud security fundamentals (focused on internal/corporate environments)
Experience mitigating data leakage risks, including AI tool misuse and shadow IT
Ability to clearly separate and coordinate with product/platform engineering responsibilities
Desirable
Experience with ISO 27001, NIST 800, or Cyber Essentials (plus)
Familiarity with GxP, or regulated environments
Experience supporting audits or certification processes
Exposure to scientific or data-intensive organisations
Relevant certifications (CISSP, CISM, cloud security)
We offer a competitive salary and benefits package. If you are passionate about developing cutting-edge scientific tools and want to contribute to breakthrough innovations in proteomics, we encourage you to apply!
- Team
- Bioinformatics (BiX)
- Role
- Director of IT
- Locations
- London
- Remote status
- Hybrid
About Portal Biotech
Founded by DNA-sequencing veterans, Portal Biotech is developing the first bench-top single-molecule protein sequencer, leveraging machine-learning algorithms and building on decades of in-house expertise in nanopore technology. By analysing full-length protein molecules at the single-molecule level, our platform delivers rapid, real-time information on protein identity, abundance, and structure. Those insights open frontiers in drug discovery, diagnostics, and fundamental research, helping scientists and clinicians to better understand human health and disease.